Teucrium polium Extract Enhances the Anti-Angiogenesis Effect of Tranilast on Human Umbilical Vein Endothelial Cells
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چکیده
منابع مشابه
Comparative Study of Anti-Cancer Properties of Hydroalcoholic Extract of Different Cultivars of Apricot Kernels on Breast Cancer Cells (MCF7) and Human Umbilical Vein Endothelial Cells
Background and purpose: Breast cancer mortality is growing around the world due to chemotherapy resistance and chemo-related side effects. Many natural products from plants are recognized to exert anticancer activity. This study aimed at investigating anti-proliferative and apoptotic activity of hydro-alcoholic extract of different varieties of apricot kernels (Jahangiri, Palmia, Jafari, and N5...
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Objective(s)Metformin is well known for activation of AMP-activated protein kinase (AMPK). AMPK activation inhibits mammalian target of rapamycin (mTOR) as a key signaling process in cell proliferation. Recent epidemiological studies demonstrate that metformin lowers the risk for several types of cancer in diabetic patients. Concerning the critical role of angiogenesis in the incidence and prog...
متن کاملAnti-Angiogenic Activity of Ficus carica Latex Extract on Human Umbilical Vein Endothelial Cells
Angiogenesis, the formation of new blood vessels, is a key process in cancer development and metastasis. In this study, the anti-angiogenic and anti-proliferative potentials of Ficus carica latex extract have been investigated using human umbilical vein endothelial cells (HUVECs). Different doses of latex extract were prepared and added to a three-dimensional culture of HUVEC in a collagen matr...
متن کاملThe Effect of Teucrium Polium Boiled Extract in Diabetic Rats
OBJECTIVE: In traditional medicaments, Teucrium Polium is used as anti-fungal, antibacterial, anti-inflammatory and antidiabetic. Modern researches have shown that use of T. polium in vitro leads to decrease in fatty acids. To confirm the anti-diabetic evidences of Teucrium polium this survey was done to evaluate the effect of boiled aqueous extract of T. polium on serum lipids, body weight and...
متن کاملExtract of Artemisia lavandulaefolia Inhibits In Vitro Angiogenesis in Human Umbilical Vein Endothelial Cells
Angiogenesis is important processes for tumor growth and metastasis. Anti-angiogenesis target therapy has recently been known to be new anti-cancer therapeutic strategies. Natural products such as traditional medicine comprise a major source of angiogenesis inhibitors. Artemisia lavandulaefolia has been known to use in the traditional medical practices. However, its molecular mechanism on the t...
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ژورنال
عنوان ژورنال: Advanced Pharmaceutical Bulletin
سال: 2018
ISSN: 2228-5881,2251-7308
DOI: 10.15171/apb.2018.016